PGC anticorps (AA 21-120) (Biotin)

N° du produit ABIN731215

Cet anticorps Lapin Polyclonal détecte spécifiquement PGC dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour PGC anticorps (AA 21-120) (Biotin) (ABIN731215)

Antigène: PGC (Pepsinogen C (PGC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGC est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PGC anticorps (Biotin)

Épitope: AA 21-120

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PG-C

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PGC

Antigène: PGC (Pepsinogen C (PGC))

Autre désignation: PG-C/Pepsinogen 2

Sujet:

Synonyms: PEPC, PGII, Gastricsin, Pepsinogen C, PGC

Background: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq].

ID gène: 5225

UniProt: P20142