PFN1 anticorps (AA 41-140)
Aperçu rapide pour PFN1 anticorps (AA 41-140) (ABIN731288)
Antigène
Voir toutes PFN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 41-140
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Réactivité croisée
- Humain, Souris, Rat
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Homologie
- Dog,Cow,Horse
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human Profilin 1
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- PFN1 (Profilin 1 (PFN1))
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Autre désignation
- Profilin 1
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Sujet
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Synonyms: ALS18, Profilin-1, Epididymis tissue protein Li 184a, Profilin I, PFN1
Background: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
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ID gène
- 5216
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UniProt
- P07737
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Pathways
- Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location
Antigène
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