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ABO (Blood Group Antigen B) anticorps (Biotin)

Cet anticorps anti- est un anticorps Souris Monoclonal détectant dans IHC et IHC (fp). Adapté pour Humain.
N° du produit ABIN7649070

Aperçu rapide pour ABO (Blood Group Antigen B) anticorps (Biotin) (ABIN7649070)

Antigène

ABO (Blood Group Antigen B)

Reactivité

Humain

Hôte

  • 16
Souris

Clonalité

  • 16
Monoclonal

Conjugué

  • 9
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Biotin

Application

  • 11
  • 10
  • 5
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone

HEB-20
  • Fonction

    Blood Group Antigen B (CD173)(HEB-20), Biotin conjugate

    Attributs du produit

    This antibody is applicable for staining ABO blood groups B and AB. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens. This antibody shows specific staining of erythrocytes and vascular epithelium of blood group B controls and no staining in group A controls. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Mixture of erythrocytes of group B and glyco protein fraction isolated from saliva of secretors with blood group B

    Isotype

    IgG1, kappa
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    Positive Control: KG1 cells. Human colorectal carcinoma tissues.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % BSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    ABO (Blood Group Antigen B)

    Autre désignation

    Blood Group B

    Sujet

    Synonyms: ABO Type B, Blood Group B

    Gene Symbol: ABO

    Poids moléculaire

    Multiple

    ID gène

    28

    UniProt

    P16442
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