Cathepsin K anticorps (AA 163-274) (Biotin)

N° du produit ABIN7650716

L’anticorps Souris Monoclonal anti-Cathepsin K a été validé pour IHC et IHC (fp). Il convient pour détecter Cathepsin K dans des échantillons de Humain.

Aperçu rapide pour Cathepsin K anticorps (AA 163-274) (Biotin) (ABIN7650716)

Antigène: Cathepsin K (CTSK)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cathepsin K est conjugé à/à la Biotin

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: CTSK-2791

Détail du produit anti-Cathepsin K anticorps (Biotin)

Épitope: AA 163-274

Fonction: Cathepsin K (Marker of Tumor Invasiveness)(CTSK/2791), Biotin conjugate

Attributs du produit: Cathepsin K is a lysosomal and secreted cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant fragment of human Cathepsin K protein (around aa 163-274)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: Human liver or breast tissue (IHC).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur Cathepsin K

Antigène: Cathepsin K (CTSK)

Autre désignation: Cathepsin K

Sujet:

Synonyms: Cathepsin K, Cathepsin O, Cathepsin O1, Cathepsin O2, Cathepsin X, CTSK

Gene Symbol: CTSK

Poids moléculaire: 39 kDa

ID gène: 1513

UniProt: P43235

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades