CD207 anticorps (AA 74-213) (CF®405S)

N° du produit ABIN7650948

Cet anticorps anti-CD207 est un anticorps Souris Monoclonal détectant CD207 dans . Adapté pour Humain.

Aperçu rapide pour CD207 anticorps (AA 74-213) (CF®405S) (ABIN7650948)

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD207 est conjugé à/à la CF®405S

Application: Veuillez nous consulter SVP

Clone: LGRN-1821

Détail du produit anti-CD207 anticorps (CF®405S)

Épitope: AA 74-213

Fonction: Langerin / CD207 (Marker of Langerhans Cells)(LGRN/1821), CF405S conjugate

Attributs du produit: Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2 -dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant fragment (around aa74-213) of human Langerin protein

Isotype: IgG2a, kappa

Information d'application

Indications d'application: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Commentaires:

Positive Control: HeLa or A549 cells (WB).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur CD207

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Autre désignation: CD207

Sujet:

Synonyms: C-type lectin domain family 4 member K, CD207, CLEC4K, Langerhans cell specific c type lectin, Langerin

Gene Symbol: CD207

Tissue Expression: Heart|Lymph node|Dendritic cells|Liver|Lung|Spleen|Thymus

Poids moléculaire: 48 kDa

ID gène: 50489

UniProt: Q9UJ71