Recombinant DC-SIGN/CD209 anticorps (CF®488A)

N° du produit ABIN7650990

Cet anticorps anti-DC-SIGN/CD209 est un anticorps Souris Monoclonal détectant DC-SIGN/CD209 dans IHC et IHC (fp). Adapté pour Humain.

Aperçu rapide pour Recombinant DC-SIGN/CD209 anticorps (CF®488A) (ABIN7650990)

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DC-SIGN/CD209 est conjugé à/à la CF®488A

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: RC209-1781

Détail du produit anti-DC-SIGN/CD209 anticorps (CF®488A)

Fonction: CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells)(rC209/1781), CF488A conjugate

Attributs du produit: DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human CD209 protein fragment

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: THP-1 or HeLa cells (IF/FACS). Human liver or spleen lysate (WB). Human small intestine (IHC).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur DC-SIGN/CD209

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Autre désignation: CD209

Sujet:

Synonyms: CD209, CDSIGN, CIRE, CLEC4L, DC-SIGN, DC-SIGN1, DCSIGN, Dendritic cell-specific ICAM-3 Grabbing Non-integrin 1, HIV GP120 Binding Protein, SIGN-R1, SIGNR5

Gene Symbol: CD209

Tissue Expression: Antigen presenting cells|Monocytes/macrophages|Myeloid cells

Poids moléculaire: 45 kDa

ID gène: 30835

UniProt: Q9NNX6