CD6 anticorps (CF®647)
Aperçu rapide pour CD6 anticorps (CF®647) (ABIN7651723)
Antigène
Voir toutes CD6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- CD6 (Negative Marker of T-regulatory Cells)(SPV-L14), CF647 conjugate
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Attributs du produit
- CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
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Immunogène
- CD8 cytotoxic T-cell clone
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Isotype
- IgG1, kappa
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Indications d'application
- Flow cytometry: 1-2 μg/mL. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user
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Commentaires
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Positive Control: CCRF-CEM, Jurkat cells, Tonsil
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % BSA, 0.05 % azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from light
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Stock
- 4 °C
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Stockage commentaire
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Date de péremption
- 24 months
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- CD6
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Autre désignation
- CD6
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Sujet
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Synonyms: T12, TP120
Gene Symbol: CD6
Tissue Expression: B-cells|T-cells
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Poids moléculaire
- 90-130 kDa
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ID gène
- 923
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UniProt
- P30203
Antigène
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