Cytochrome P450 anticorps (C-Term) (CF®740)

N° du produit ABIN7653008

L’anticorps Souris Monoclonal anti-Cytochrome P450 a été validé pour IHC et IHC (fp). Il convient pour détecter Cytochrome P450 dans des échantillons de Humain.

Aperçu rapide pour Cytochrome P450 anticorps (C-Term) (CF®740) (ABIN7653008)

Antigène: Cytochrome P450 (CYP)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytochrome P450 est conjugé à/à la CF®740

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: M12P4H2

Détail du produit anti-Cytochrome P450 anticorps (CF®740)

Épitope: C-Term

Fonction: Cytochrome p450(M12P4H2), CF740 conjugate

Attributs du produit: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases, which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines, which are pre-mutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Ovalbumin-conjugated synthetic peptide HIGFGCIPPR (C-terminal sequence)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: HepG2 cells. Liver.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur Cytochrome P450

Antigène: Cytochrome P450 (CYP)

Autre désignation: Cytochrome p450

Sujet:

Synonyms: 4-nitrophenol 2-hydroxylase, CPE1, CYP2Ecytochrome P450 2E1, CYPIIE1, cytochrome P450, family 2, subfamily E, polypeptide 1, cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1 , Cytochrome P450-J, EC 1.14.13, EC 1.14.13.n7, EC 1.14.14.1, flavoprotein-linked monooxygenase, microsomal monooxygenase, P450C2E, P450-J, xenobiotic monooxygenase

Gene Symbol: CYP2E1

Poids moléculaire: ~50-55 kDa

ID gène: 1571

UniProt: P05181

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process