PDCD4 anticorps (AA 1-100)
Aperçu rapide pour PDCD4 anticorps (AA 1-100) (ABIN731993)
Antigène
Voir toutes PDCD4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-100
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human PDCD4
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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: "The relevance of miRNA-21 in HSV-induced inflammation in a mouse model." dans: International journal of molecular sciences, Vol. 16, Issue 4, pp. 7413-27, (2015) (PubMed).
: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." dans: International journal of nanomedicine, Vol. 9, pp. 4829-46, (2014) (PubMed).
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: "The relevance of miRNA-21 in HSV-induced inflammation in a mouse model." dans: International journal of molecular sciences, Vol. 16, Issue 4, pp. 7413-27, (2015) (PubMed).
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- PDCD4 (Programmed Cell Death 4 (PDCD4))
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Autre désignation
- PDCD4
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Sujet
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Synonyms: H731, Programmed cell death protein 4, Neoplastic transformation inhibitor protein, Nuclear antigen H731-like, Protein 197/15a, PDCD4
Background: Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).
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ID gène
- 27250
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UniProt
- Q53EL6
Antigène
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