Cathepsin K anticorps

N° du produit ABIN732038

L’anticorps Lapin Polyclonal anti-Cathepsin K a été validé pour WB. Il convient pour détecter Cathepsin K dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Cathepsin K anticorps (ABIN732038)

Antigène: Cathepsin K (CTSK)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin K est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cathepsin K anticorps

Réactivité croisée: Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Capsin K

Isotype: IgG

Information d'application

Indications d'application: WB: 1:100-1000, IHC-P: 1:100-500, IF(IHC-P): 1:50-200
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Cathepsin K

Antigène: Cathepsin K (CTSK)

Autre désignation: Cathepsin K

Sujet:

Synonyms: Cathepsin K, Procathepsin K, Cathepsin K precursor, Cathepsin O, Cathepsin O1, Cathepsin O2, Cathepsin X, CathepsinK, CTS02, CTSK, CTSK protein, CTSO, CTSO1, CTSO2, MGC23107, PKND, PYCD, Pycnodysostosis, cath-K, CK.

Background: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq, Jul 2008].

ID gène: 1513

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades