FTL anticorps (AA 38-165) (CF®594)

N° du produit ABIN7654020

Cet anticorps anti-FTL est un anticorps Souris Monoclonal détectant FTL dans WB, IHC et IHC (fp). Adapté pour Humain.

Aperçu rapide pour FTL anticorps (AA 38-165) (CF®594) (ABIN7654020)

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FTL est conjugé à/à la CF®594

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: FTL-1387

Détail du produit anti-FTL anticorps (CF®594)

Épitope: AA 38-165

Fonction: Ferritin, Light Chain (FTL) (Microglia Marker) (FTL/1387), CF594 conjugate

Attributs du produit: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant fragment (around aa 38-165) of human FTL protein

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Cerebellum or Testis.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur FTL

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Autre désignation: Ferritin, Light Chain

Sujet:

Synonyms: Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3

Gene Symbol: FTL

Poids moléculaire: 19-25 kDa

ID gène: 2512

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis