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Fibronectin anticorps (AA 467-595) (CF®405S)

L’anticorps Souris Monoclonal anti-Fibronectin a été validé pour . Il convient pour détecter Fibronectin dans des échantillons de Humain.
N° du produit ABIN7654037

Aperçu rapide pour Fibronectin anticorps (AA 467-595) (CF®405S) (ABIN7654037)

Antigène

Voir toutes Fibronectin Anticorps
Fibronectin

Reactivité

  • 141
  • 58
  • 56
  • 26
  • 15
  • 9
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
Humain

Hôte

  • 91
  • 86
  • 5
  • 2
Souris

Clonalité

  • 101
  • 81
  • 1
Monoclonal

Conjugué

  • 77
  • 27
  • 10
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Fibronectin est conjugé à/à la CF®405S

Application

Veuillez nous consulter SVP

Clone

FN1-2949
  • Épitope

    • 15
    • 15
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 467-595

    Fonction

    Fibronectin(FN1/2949), CF405S conjugate

    Attributs du produit

    Fibronectins are disulfide-linked, dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin, but not plasma fibronectin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Recombinant fragment (around aa 467-595) of human fibronectin protein

    Isotype

    IgG1, kappa
  • Indications d'application

    For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

    Commentaires

    Positive Control: SW156 cells or Kidney

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % BSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    Fibronectin

    Sujet

    Synonyms: Cold insoluble globulin (CIG), FINC, FN1, FNZ, GFND, GFND2, LETS, Migration stimulating factor (MSF), Ugl-Y3

    Gene Symbol: FN1

    Poids moléculaire

    220 kDa (monomer), 440 kDa (dimer)

    ID gène

    2335

    UniProt

    P02751
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