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FSHB anticorps (CF®740)

Cet anticorps anti-FSHB est un anticorps Souris Monoclonal détectant FSHB dans IHC et IHC (fp). Adapté pour Humain.
N° du produit ABIN7654182

Aperçu rapide pour FSHB anticorps (CF®740) (ABIN7654182)

Antigène

Voir toutes FSHB Anticorps
FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))

Reactivité

  • 92
  • 29
  • 16
  • 7
  • 4
  • 2
  • 1
Humain

Hôte

  • 64
  • 48
Souris

Clonalité

  • 61
  • 51
Monoclonal

Conjugué

  • 56
  • 7
  • 7
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp FSHB est conjugé à/à la CF®740

Application

  • 73
  • 44
  • 24
  • 22
  • 21
  • 17
  • 13
  • 13
  • 11
  • 10
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone

FSHb-1062
  • Fonction

    FSH beta(FSHb/1062), CF740 conjugate

    Attributs du produit

    This MAb reacts with a protein of 22 kDa, identified as beta sub-unit of FSH. It does not cross react with the alpha sub-unit. Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Recombinant hFSH beta sub-unit

    Isotype

    IgG1, kappa
  • Indications d'application

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. Immunohistology formalin-fixed 0.5-1 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user

    Commentaires

    Positive Control: Anterior Pituitary

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % rBSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))

    Autre désignation

    FSH-Beta

    Sujet

    Synonyms: Follicle stimulating hormone beta polypeptide, Follicle stimulating hormone beta subunit, Follitropin beta chain, Follitropin subunit beta, FSH-B, FSH-beta, FSHB, FSHbeta

    Gene Symbol: FSHB

    Poids moléculaire

    22 kDa

    ID gène

    2488

    UniProt

    P01225

    Pathways

    Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process
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