Gastrin anticorps (CF®647)

N° du produit ABIN7654256

L’anticorps Souris Monoclonal anti-Gastrin a été validé pour . Il convient pour détecter Gastrin dans des échantillons de Humain.

Aperçu rapide pour Gastrin anticorps (CF®647) (ABIN7654256)

Antigène: Gastrin (GAST)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Gastrin est conjugé à/à la CF®647

Application: Veuillez nous consulter SVP

Clone: GAST-2631

Détail du produit anti-Gastrin anticorps (CF®647)

Fonction: Gastrin(GAST/2631), CF647 conjugate

Attributs du produit: Gastrin, is a hormone that normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets. Its primary function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. It also responsible for stimulating smooth muscle contraction and increasing blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger-Ellison syndrome. Gastrin-Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones and also acts as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant full-length human GAST protein

Isotype: IgG2c, kappa

Information d'application

Indications d'application: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Commentaires:

Positive Control: Human Pituitary or Stomach.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur Gastrin

Antigène: Gastrin (GAST)

Autre désignation: Gastrin

Sujet:

Synonyms: Component II, GAS, Gast, Gastrin component I, Gastrin component II, Gastrin component III, Gastrin precursor, Gastrin-14, Gastrin-17, Gastrin-34, Gastrin-52, Gastrin-6, Gastrin-71

Gene Symbol: GAST

Tissue Expression: Pancreatic islet cells|Stomach

Poids moléculaire: 2/4/14 kDa

ID gène: 2520

UniProt: P01350