Human Papilloma Virus 16 E2 (HPV-16 E2) anticorps (CF®640R)

N° du produit ABIN7655165

L’anticorps anti-Human Papilloma Virus 16 E2 Monoclonal Souris est utilisé pour la détection de Human Papilloma Virus 16 E2 dans des échantillons de Human Papillomavirus 16 (HPV-16). Il a été validé pour WB et IF.

Aperçu rapide pour Human Papilloma Virus 16 E2 (HPV-16 E2) anticorps (CF®640R) (ABIN7655165)

Antigène: Human Papilloma Virus 16 E2 (HPV-16 E2)

Reactivité: Human Papillomavirus 16 (HPV-16)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: CF®640R

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: TVG 261

Détail du produit

Fonction: HPV16 E2 (Human Papilloma Virus 16)(TVG 261), CF640R conjugate

Attributs du produit: The human papilloma virus (HPV) family of DNA tumor viruses includes HPV16, a strain that is responsible for the largest number of cases of cervical cancers linked to the family. HPV16E1 and HPV16E2 are proteins that are involved in the regulation of viral DNA replication and are important for infected cell homeostasis. HPV16E2 specifically regulates the expression of the E6 and E7 oncoproteins by binding to four sites within the viral long control region, possibly involving interactions with nuclear hormone receptors. Integration of the HPV genome into the host DNA usually disrupts the HPV16E2 gene open reading frames, resulting in an overexpression of E6 and E7 genes, an event that may lead to the malignant transformation of cervical cancer. HPV16E2 is also able to induce apoptotic cell death via two pathways: the first through the binding of p53 and the second through the binding of the viral genome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Raised against Vaccinia-E2 followed by intravenous injection of the maltose binding protein MBP-E2

Isotype: IgG1, kappa

Information d'application

Indications d'application: Western blot 1-2 μg/mL, Optimal dilution for a specific application should be determined.

Commentaires:

Positive Control: HPV-16 infected cells. Cervical tissue.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détail du antigène

Antigène: Human Papilloma Virus 16 E2 (HPV-16 E2)

Autre désignation: HPV16 E2

Classe de substances: Viral Protein

Sujet:

Synonyms: HPV16 regulatory protein E2, Human papilloma virus 16 E2, Human papilloma virus 16 regulatory protein E2, Human papillomavirus type 16 E2, Human papillomavirus type 16 regulatory protein E2, Regulatory protein E2

Gene Symbol: Not Applicable

Poids moléculaire: 43 kDa