IL-10RA anticorps

N° du produit ABIN7655658

Cet anticorps anti-IL-10RA est un anticorps Rat Monoclonal détectant IL-10RA dans FACS et Func. Adapté pour Souris.

Aperçu rapide pour IL-10RA anticorps (ABIN7655658)

Antigène: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-10RA est non-conjugé

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: 1B1-3a

Détail du produit anti-IL-10RA anticorps

Fonction: IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210)(1B1.3a)

Attributs du produit: This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110 kDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Purified recombinant extracellular region of Mouse IL10RA

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: MPBMC . Spleen, Thymus, Lymph Node, Placenta, Lung or Liver.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur IL-10RA

Antigène: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Autre désignation: IL-10R1

Sujet:

Synonyms: CD210 antigen, CDw210a, IBD28, IL10R alpha, IL-10R subunit 1, IL-10R1, IL10RA IL10RIL-10R subunit alpha, interleukin 10 receptor, alpha, interleukin-10 receptor alpha chain, Interleukin-10 receptor subunit 1

Tissue Expression: Lymphocytes|Monocytes/macrophages|NK cells

Poids moléculaire: 90-110 kDa

ID gène: 16154

UniProt: Q61727

Pathways: Growth Factor Binding