LI Cadherin anticorps (AA 242-418) (Biotin)

N° du produit ABIN7656361

Cet anticorps Souris Monoclonal détecte spécifiquement LI Cadherin dans IHC, IHC (fp) et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour LI Cadherin anticorps (AA 242-418) (Biotin) (ABIN7656361)

Antigène: LI Cadherin

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LI Cadherin est conjugé à/à la Biotin

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Flow Cytometry (FACS)

Clone: CDH17-2618

Détail du produit anti-LI Cadherin anticorps (Biotin)

Épitope: AA 242-418

Fonction: Cadherin 17 / LI Cadherin (Liver-Intestine Marker)(CDH17/2618), Biotin conjugate

Attributs du produit: Cadherin 17, also known as LI cadherin (for liver-intestine cadherin), is a member of the cadherin family of calcium-dependent adhesion molecules. Cadherins mediate cell-cell interactions via hemophilic binding, and are critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. Cadherin 17 expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17)

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: MCF-7, HepG2 or HT29 cells. Stomach, Small Intestine, Colon or liver.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur LI Cadherin

Antigène: LI Cadherin

Autre désignation: Cadherin 17

Sujet:

Synonyms: Cadherin 17, Cadherin-17, CDH17, LI-cadherin, Liver-intestine cadherin, human peptide transporter 1 (HPT-1), Intestinal peptide-associated transporter HPT-1

Gene Symbol: CDH17

Tissue Expression: Intestine|Liver

Poids moléculaire: 120 kDa

ID gène: 1015

UniProt: Q12864