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Mammaglobin anticorps (CF®405S)

Cet anticorps Souris Monoclonal détecte spécifiquement Mammaglobin dans IHC, WB et IHC (fp). Il présente une réactivité envers Humain.
N° du produit ABIN7656520

Aperçu rapide pour Mammaglobin anticorps (CF®405S) (ABIN7656520)

Antigène

Mammaglobin

Reactivité

  • 41
  • 9
  • 1
Humain

Hôte

  • 33
  • 9
Souris

Clonalité

  • 30
  • 12
Monoclonal

Conjugué

  • 12
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Mammaglobin est conjugé à/à la CF®405S

Application

  • 34
  • 29
  • 24
  • 12
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone

MGB1-2000
  • Fonction

    Mammaglobin (SCGB2A2) (Breast Cancer Marker) (MGB1/2000), CF405S conjugate

    Attributs du produit

    Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues. Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Recombinant full-length human Mammaglobin (SCGB2A2) protein

    Isotype

    IgG1, kappa
  • Indications d'application

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 0.1-0.2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

    Commentaires

    Positive Control: SK-BR-3 cells or Breast Carcinoma

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % BSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    Mammaglobin

    Sujet

    Synonyms: Mammaglobin-1 (MGB1), Mammaglobin-A, Secretoglobin family 2A member 2 (SCGB2A2), SG2A2, UGB2

    Gene Symbol: SCGB2A2

    Tissue Expression: Mammary gland

    Poids moléculaire

    18 kDa

    ID gène

    4250

    UniProt

    Q13296
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