Recombinant TIMP2 anticorps (N-Term) (Biotin)

N° du produit ABIN7657002

Cet anticorps anti-TIMP2 est un anticorps Souris Monoclonal détectant TIMP2 dans IHC et IHC (fp). Adapté pour Humain, Rat, Souris, Boeuf (Vache), Poisson zèbre (Danio rerio), Lapin et Cobaye.

Aperçu rapide pour Recombinant TIMP2 anticorps (N-Term) (Biotin) (ABIN7657002)

Antigène: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Poisson zèbre (Danio rerio), Lapin, Cobaye

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TIMP2 est conjugé à/à la Biotin

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: RTIMP2-2335

Détail du produit anti-TIMP2 anticorps (Biotin)

Épitope: AA 56-66, N-Term

Fonction: TIMP2 (Tissue Inhibitor of Metalloproteinase 2)(rTIMP2/2335), Biotin conjugate

Attributs du produit: Recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: A synthetic peptide from the N-terminus of human TIMP2 protein (aa56-66) (DSGNDIYGNPI)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: HeLa cells. Normal Placenta. Breast, Colon, Endometrial, Prostate or Ovarian Carcinoma.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur TIMP2

Antigène: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Autre désignation: TIMP2

Sujet:

Synonyms: Metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, TIMP2, Tissue Inhibitor of Metalloproteinase 2

Gene Symbol: TIMP2

Poids moléculaire: 21 kDa

ID gène: 7077

UniProt: P16035

Pathways: cAMP Metabolic Process