Recombinant TIMP2 anticorps (N-Term)
Aperçu rapide pour Recombinant TIMP2 anticorps (N-Term) (ABIN7657008)
Antigène
Voir toutes TIMP2 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 56-66, N-Term
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Fonction
- TIMP2 (Tissue Inhibitor of Metalloproteinase 2)(rTIMP2/2335)
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Attributs du produit
- Recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogène
- A synthetic peptide from the N-terminus of human TIMP2 protein (aa56-66) (DSGNDIYGNPI)
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Positive Control: HeLa cells. Normal Placenta. Breast, Colon, Endometrial, Prostate or Ovarian Carcinoma.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, no BSA, no azide
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Agent conservateur
- Without preservative
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Stock
- -20 °C
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Stockage commentaire
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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Date de péremption
- 24 months
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- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
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Autre désignation
- TIMP2
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Sujet
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Synonyms: Metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, TIMP2, Tissue Inhibitor of Metalloproteinase 2
Gene Symbol: TIMP2
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Poids moléculaire
- 21 kDa
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ID gène
- 7077
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UniProt
- P16035
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Pathways
- cAMP Metabolic Process
Antigène
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