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Recombinant CD56 anticorps (CF®640R)

Cet anticorps anti-CD56 est un anticorps Lapin Monoclonal détectant CD56 dans FACS, IHC et IHC (fp). Adapté pour Humain.
N° du produit ABIN7657821

Aperçu rapide pour Recombinant CD56 anticorps (CF®640R) (ABIN7657821)

Antigène

Voir toutes CD56 (NCAM1) Anticorps
CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Type d'anticorp

Recombinant Antibody

Reactivité

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  • 85
  • 72
  • 24
  • 19
  • 12
  • 10
  • 9
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  • 5
  • 2
  • 2
  • 1
Humain

Hôte

  • 208
  • 110
  • 4
  • 2
  • 1
  • 1
Lapin

Clonalité

  • 235
  • 85
  • 4
  • 2
Monoclonal

Conjugué

  • 108
  • 17
  • 15
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  • 13
  • 8
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  • 7
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  • 1
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Cet anticorp CD56 est conjugé à/à la CF®640R

Application

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone

NCAM1-2217R
  • Fonction

    CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) (NCAM1/2217R), CF640R conjugate

    Attributs du produit

    This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Recombinant full-length human NCAM1 (CD56) protein

    Isotype

    IgG
  • Indications d'application

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 0.5-1 μg/mL

    Commentaires

    Positive Control: Colon or Small Intestine

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % BSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

    Autre désignation

    CD56

    Sujet

    Synonyms: NCAM, Leu-19, NKH1, MSK39, NCAM120, NCAM140, NCAM180, Neural Cell Adhesion Molecule

    Gene Symbol: NCAM1

    Tissue Expression: Skeletal Muscle|Neurons|NK cells

    Poids moléculaire

    180, 145 and 125 kDa

    ID gène

    4684

    UniProt

    P13591, P13592
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