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ERK1/2 anticorps (pThr183, pTyr185)

MAPK1/3 Reactivité: Humain, Souris, Rat, Poulet WB, ELISA, IHC (p), IF (cc), FACS, IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN732458
  • Antigène Voir toutes ERK1/2 (MAPK1/3) Anticorps
    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
    Épitope
    • 56
    • 41
    • 29
    • 29
    • 16
    • 12
    • 12
    • 10
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr183, pTyr185
    Reactivité
    • 199
    • 169
    • 166
    • 23
    • 22
    • 18
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Poulet
    Hôte
    • 143
    • 58
    • 4
    Lapin
    Clonalité
    • 139
    • 66
    Polyclonal
    Conjugué
    • 99
    • 12
    • 9
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ERK1/2 est non-conjugé
    Application
    • 157
    • 64
    • 50
    • 50
    • 49
    • 37
    • 25
    • 23
    • 22
    • 12
    • 7
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Poulet, Humain, Souris, Rat
    Homologie
    Dog,Cow,Pig,Horse,Rabbit,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic phosphopeptide derived from human ERK2 around the phosphorylation site of Thr183/Tyr185
    Isotype
    IgG
    Top Product
    Discover our top product MAPK1/3 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Hirata, Katayama, Tsuji, Imura, Natsume, Sugahara, Kunieda, Nakamura, Otsuki: "Homeobox family Hoxc localization during murine palate formation." dans: Congenital anomalies, Vol. 56, Issue 4, pp. 172-9, (2016) (PubMed).

    Iriyama, Hatta, Takei: "Direct effect of dasatinib on signal transduction pathways associated with a rapid mobilization of cytotoxic lymphocytes." dans: Cancer medicine, Vol. 5, Issue 11, pp. 3223-3234, (2016) (PubMed).

    Wang, Fu, Jiang, Yu, Wang, Han, Liu, Wang: "Bone marrow mononuclear cell transplantation promotes therapeutic angiogenesis via upregulation of the VEGF-VEGFR2 signaling pathway in a rat model of vascular dementia." dans: Behavioural brain research, Vol. 265, pp. 171-80, (2014) (PubMed).

  • Antigène
    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
    Autre désignation
    ERK1+ERK2 (MAPK1/3 Produits)
    Synonymes
    anticorps erk1/2, anticorps mitogen-activated protein kinase, anticorps erk1/2
    Sujet

    Synonyms: ERK, p38, p4, p41, ERK2, ERT1, ERK-2, MAPK2, PRKM1, PRKM2, P42MAPK, p41mapk, p42-MAPK, ERK1, ERT2, ERK-1, PRKM3, P44ERK1, P44MAPK, HS44KDAP, HUMKER1A, p44-ERK1, p44-MAPK, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, Extracellular signal-regulated kinase 2, MAP kinase isoform p42, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, MAPK1

    Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

    ID gène
    55945595
    UniProt
    P28482
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