P-Cadherin anticorps (CF®740)

N° du produit ABIN7658270

L’anticorps Souris Monoclonal anti-P-Cadherin a été validé pour WB et IF. Il convient pour détecter P-Cadherin dans des échantillons de Humain.

Aperçu rapide pour P-Cadherin anticorps (CF®740) (ABIN7658270)

Antigène: P-Cadherin (CDH3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp P-Cadherin est conjugé à/à la CF®740

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 12H6

Détail du produit anti-P-Cadherin anticorps (CF®740)

Fonction: P-Cadherin (CDH3) (12H6), CF740 conjugate

Attributs du produit: This antibody recognizes a protein of 116 kDa, identified as P-Cadherin-1 (CDH3). It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human full-length P-cadherin fusion protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user

Commentaires:

Positive Control: A431 or PC-3 cells. Pancreas, Placenta or Prostate

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur P-Cadherin

Antigène: P-Cadherin (CDH3)

Autre désignation: P-Cadherin

Sujet:

Synonyms: Cadherin 3 type 1, Cadherin-3, Cadp, Calcium dependent adhesion protein placental, CDH3, CDHP, HJMD, P-cadherin (Placental), PCAD, Placental cadherin

Gene Symbol: CDH3

Tissue Expression: Epithelial cells

Poids moléculaire: 116 kDa

ID gène: 1001

UniProt: P22223