PAX5 anticorps (AA 235-382) (CF®405S)

N° du produit ABIN7658288

L’anticorps Souris Monoclonal anti-PAX5 a été validé pour WB, IHC et IHC (fp). Il convient pour détecter PAX5 dans des échantillons de Humain.

Aperçu rapide pour PAX5 anticorps (AA 235-382) (CF®405S) (ABIN7658288)

Antigène: PAX5 (Paired Box 5 (PAX5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PAX5 est conjugé à/à la CF®405S

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: PAX5-3735

Détail du produit anti-PAX5 anticorps (CF®405S)

Épitope: AA 235-382

Fonction: PAX5 / BSAP (Early B-Cell Marker)(PAX5/3735), CF405S conjugate

Attributs du produit: The specificity of this monoclonal antibody to its intended target was validated by HuProt™, Array, containing more than 21, 000, full-length human proteins. The PAX5 gene is a member of thepaired box (PAX)family of transcription factors. The central feature of this gene family is a novel, highly conservedDNA-binding domain, known as thepaired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute toneoplastic transformation. The PAX5 gene encodes theB-celllineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development andspermatogenesis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: A recombinant fragment (around aa 235-382) of human PAX5 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: DAUDI or Ramos Cells. Tonsil, spleen, Lymph Node or Colon Carcinoma.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur PAX5

Antigène: PAX5 (Paired Box 5 (PAX5))

Autre désignation: BSAP

Sujet:

Synonyms: B cell lineage specific activator, BSAP, EBB-1, KLP, Paired box 5

Gene Symbol: PAX5

Tissue Expression: B-cells

Poids moléculaire: 42 kDa

ID gène: 5079

UniProt: Q02548