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PAX7 anticorps (AA 300-600) (CF®740)

L’anticorps Souris Monoclonal anti-PAX7 a été validé pour WB. Il convient pour détecter PAX7 dans des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio) et Poulet.
N° du produit ABIN7658345

Aperçu rapide pour PAX7 anticorps (AA 300-600) (CF®740) (ABIN7658345)

Antigène

Voir toutes PAX7 Anticorps
PAX7 (Paired Box 7 (PAX7))

Reactivité

  • 108
  • 65
  • 50
  • 17
  • 15
  • 8
  • 8
  • 7
  • 7
  • 4
  • 3
  • 3
  • 1
  • 1
Humain, Souris, Rat, Poisson zèbre (Danio rerio), Poulet

Hôte

  • 72
  • 40
  • 1
  • 1
Souris

Clonalité

  • 64
  • 50
Monoclonal

Conjugué

  • 54
  • 7
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp PAX7 est conjugé à/à la CF®740

Application

  • 84
  • 33
  • 33
  • 32
  • 21
  • 15
  • 13
  • 13
  • 13
  • 9
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

Clone

PAX7-497
  • Épitope

    • 22
    • 16
    • 9
    • 9
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 300-600

    Fonction

    PAX7(PAX7/497), CF740 conjugate

    Attributs du produit

    The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Recombinant fragment (aa300-600) of human PAX7 protein

    Isotype

    IgG1, kappa
  • Indications d'application

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Immunohistology (frozen) 0.5-1 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user

    Commentaires

    Positive Control: Rhabdomyosarcoma (RMS)|U2OS

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % rBSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    PAX7 (Paired Box 7 (PAX7))

    Autre désignation

    PAX7

    Sujet

    Synonyms: HUP1, Paired box gene 7, Paired box homeotic gene 7, Paired domain gene HuP1, PAX7 transcriptional factor, PAX7/FKHR fusion gene, PAX7B, RMS2

    Gene Symbol: PAX7

    Poids moléculaire

    57 kDa

    ID gène

    5081

    UniProt

    P23759
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