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Recombinant pan Keratin anticorps (basic) (CF®568)

Cet anticorps anti-pan Keratin est un anticorps Lapin Monoclonal détectant pan Keratin dans IF, IHC et IHC (fp). Adapté pour Humain, Rat et Souris.
N° du produit ABIN7658415

Aperçu rapide pour Recombinant pan Keratin anticorps (basic) (CF®568) (ABIN7658415)

Antigène

Voir toutes pan Keratin (panKRT) Anticorps
pan Keratin (panKRT)

Type d'anticorp

Recombinant Antibody

Reactivité

  • 162
  • 115
  • 95
  • 71
  • 57
  • 41
  • 41
  • 40
  • 40
  • 40
  • 30
  • 29
  • 11
  • 11
  • 10
  • 3
  • 1
  • 1
  • 1
Humain, Rat, Souris

Hôte

  • 97
  • 66
  • 3
Lapin

Clonalité

  • 131
  • 35
Monoclonal

Conjugué

  • 48
  • 15
  • 12
  • 11
  • 11
  • 11
  • 11
  • 11
  • 10
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp pan Keratin est conjugé à/à la CF®568

Application

  • 91
  • 82
  • 69
  • 68
  • 57
  • 19
  • 16
  • 14
  • 14
  • 7
  • 5
  • 5
  • 4
  • 3
  • 2
Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone

KRTH-2147R
  • Épitope

    • 31
    • 20
    • 15
    • 11
    • 1
    • 1
    • 1
    • 1
    basic

    Fonction

    Cytokeratin, Basic (Type II or HMW)(KRTH/2147R), CF568 conjugate

    Attributs du produit

    This antibody recognizes CK1, CK5, CK10 and CK14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This MAb shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands, there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this antibody. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. This antibody has also been useful in separating benign from malignant intraductal breast proliferations. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Solubilized keratin extract from human stratum corneum

    Isotype

    IgG
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    Positive Control: MCF-7, PC12 cells, Skin, Prostate carcinoma.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % BSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    pan Keratin (panKRT)

    Autre désignation

    Keratin

    Sujet

    Synonyms: KRT2B, KRT2P, HUMCYT2A, Keratin, type II Cytoskeletal 2 oral, K76, Keratin 2p (K2P), Keratin-76, Cytokeratin-2P (CK-2P, Type-II Keratin Kb9

    Gene Symbol: KRT76

    Tissue Expression: Epidermal cells|Epithelial cells

    Poids moléculaire

    50-67 kDa

    ID gène

    51350

    UniProt

    Q01546
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