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pan Keratin anticorps (High Molecular Weight) (CF®740)

L’anticorps Souris Monoclonal anti-pan Keratin a été validé pour IHC et IHC (fp). Il convient pour détecter pan Keratin dans des échantillons de Humain et Rat.
N° du produit ABIN7658426

Aperçu rapide pour pan Keratin anticorps (High Molecular Weight) (CF®740) (ABIN7658426)

Antigène

Voir toutes pan Keratin (panKRT) Anticorps
pan Keratin (panKRT)

Reactivité

  • 162
  • 116
  • 96
  • 71
  • 57
  • 41
  • 41
  • 40
  • 40
  • 40
  • 30
  • 29
  • 11
  • 11
  • 10
  • 3
  • 1
  • 1
  • 1
Humain, Rat

Hôte

  • 96
  • 67
  • 3
Souris

Clonalité

  • 131
  • 35
Monoclonal

Conjugué

  • 47
  • 15
  • 12
  • 11
  • 11
  • 11
  • 11
  • 11
  • 11
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp pan Keratin est conjugé à/à la CF®740

Application

  • 91
  • 83
  • 69
  • 69
  • 57
  • 19
  • 16
  • 14
  • 14
  • 7
  • 5
  • 5
  • 4
  • 3
  • 2
Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone

KRTH-1076
  • Épitope

    • 30
    • 21
    • 15
    • 11
    • 1
    • 1
    • 1
    • 1
    High Molecular Weight

    Fonction

    Cytokeratin, HMW(KRTH/1076), CF740 conjugate

    Attributs du produit

    This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 52 kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40 kDa. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Recombinant human KRT76 protein

    Isotype

    IgG1, kappa
  • Indications d'application

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. Western blotting 0.5-1 μg/mL. ELISA For coating, order Ab without BSA. Predicted to show broad species reactivity

    Commentaires

    Positive Control: Skin, Adenocarcinomas

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % rBSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    pan Keratin (panKRT)

    Autre désignation

    Keratin

    Sujet

    Synonyms: KRT2B, KRT2P, HUMCYT2A, Keratin, Type II Cytoskeletal 2 Oral, K2P, K76, CK-2P, Keratin 2p, Keratin-76, Cytokeratin 2, Cytokeratin-2P, Type-II Keratin Kb9

    Gene Symbol: KRT76

    Tissue Expression: Epidermal cells|Epithelial cells

    Poids moléculaire

    67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 52 kDa (CK8)

    ID gène

    51350

    UniProt

    Q01546
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