Recombinant pan Keratin anticorps (basic) (CF®740)
Aperçu rapide pour Recombinant pan Keratin anticorps (basic) (CF®740) (ABIN7658436)
Antigène
Voir toutes pan Keratin (panKRT) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- basic
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Fonction
- Cytokeratin, Basic (Type II or HMW)(KRTH/2147R), CF740 conjugate
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Attributs du produit
- This antibody recognizes CK1, CK5, CK10 and CK14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This MAb shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands, there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this antibody. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. This antibody has also been useful in separating benign from malignant intraductal breast proliferations. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogène
- Solubilized keratin extract from human stratum corneum
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Positive Control: MCF-7, PC12 cells, Skin, Prostate carcinoma.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % rBSA, 0.05 % azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from light
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Stock
- 4 °C
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Stockage commentaire
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Date de péremption
- 24 months
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- pan Keratin (panKRT)
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Autre désignation
- Keratin
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Sujet
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Synonyms: KRT2B, KRT2P, HUMCYT2A, Keratin, type II Cytoskeletal 2 oral, K76, Keratin 2p (K2P), Keratin-76, Cytokeratin-2P (CK-2P, Type-II Keratin Kb9
Gene Symbol: KRT76
Tissue Expression: Epidermal cells|Epithelial cells
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Poids moléculaire
- 50-67 kDa
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ID gène
- 51350
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UniProt
- Q01546
Antigène
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