pan Keratin anticorps (acidic)

N° du produit ABIN7658467

Cet anticorps Souris Monoclonal détecte spécifiquement pan Keratin. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Singe, Chien, Lapin, Poulet et Tortue.

Aperçu rapide pour pan Keratin anticorps (acidic) (ABIN7658467)

Antigène: pan Keratin (panKRT)

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Singe, Chien, Lapin, Poulet, Tortue

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp pan Keratin est non-conjugé

Application: Veuillez nous consulter SVP

Clone: AE-1

Détail du produit anti-pan Keratin anticorps

Épitope: acidic

Fonction: Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker)(AE-1)

Attributs du produit: This MAb recognizes the 56. 5 kDa (CK10), 50 kDa (CK14), 50 kDa (CK15), 48 kDa (CK16), 40 kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI , 48, 46, 45, and 40 kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e. g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Human epidermal keratin

Isotype: IgG1, kappa

Information d'application

Indications d'application: For coating for ELISA, order Ab without BSA. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Commentaires:

Positive Control: Skin or squamous cell carcinoma (IHC).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, no BSA, no azide

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Store at -20 °C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur pan Keratin

Antigène: pan Keratin (panKRT)

Autre désignation: Keratin

Sujet:

Synonyms: K1B, KRT1B, Keratin, type II cytoskeletal 1b, K77, CK-1B, Keratin 1B, Keratin-77, Cytokeratin-1B, Type-II Keratin Kb39

Gene Symbol: KRT77

Tissue Expression: Epidermal cells|Epithelial cells

Poids moléculaire: 40-56.5 kDa

ID gène: 374454

UniProt: Q7Z794