RPSA/Laminin Receptor anticorps

N° du produit ABIN7659650

L’anticorps Souris Monoclonal anti-RPSA/Laminin Receptor a été validé pour IF et FACS. Il convient pour détecter RPSA/Laminin Receptor dans des échantillons de Humain.

Aperçu rapide pour RPSA/Laminin Receptor anticorps (ABIN7659650)

Antigène: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RPSA/Laminin Receptor est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: RPSA-2699

Détail du produit anti-RPSA/Laminin Receptor anticorps

Fonction: Laminin Receptor / RPSA (Marker of Metastatic Potential)(RPSA/2699)

Attributs du produit: Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant full-length human RPSA protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: MCF-7, MDA-MB-453, SK-BR3, THP1, HL60, HeLa or HEK293 cells. Breast, Colon or Ovarian Carcinoma, Tonsil.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, no BSA, no azide

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Store at -20 °C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur RPSA/Laminin Receptor

Antigène: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Autre désignation: Laminin Receptor

Sujet:

Synonyms: 34/67 kDa Laminin Receptor, 37 kDa Laminin Receptor precursor, 37/67 kDa Laminin Receptor, 37LRP, 40S Ribosomal Protein SA, 67 kDa Laminin Receptor, 67LR, Colon Carcinoma Laminin-binding Protein, LAMBR, Laminin receptor 1, Laminin-binding Protein precursor p40, LAMR1, LBP/p40, LRP/LR, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, Ribosomal Protein SA (RPSA)

Gene Symbol: RPSA

Poids moléculaire: 37-67 kDa

ID gène: 3921

UniProt: P08865

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly