SPTA1 anticorps (AA 356-475) (CF®488A)

N° du produit ABIN7660111

Cet anticorps Souris Monoclonal détecte spécifiquement SPTA1 dans IHC et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour SPTA1 anticorps (AA 356-475) (CF®488A) (ABIN7660111)

Antigène: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SPTA1 est conjugé à/à la CF®488A

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: SPTA1-1810

Détail du produit anti-SPTA1 anticorps (CF®488A)

Épitope: AA 356-475

Fonction: Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate

Attributs du produit: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous i± andi² chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin i± I and spectrini² I are present in erythrocytes, whereas spectrin i± II (also designated fodrin i±) and spectrini² II (also designated fodrini²) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human SPTA fragment (around aa356-475)

Isotype: IgG2c, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: Jurkat cells. Placenta or Tonsil.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur SPTA1

Antigène: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Autre désignation: Spectrin Alpha 1

Sujet:

Synonyms: Alpha I spectrin, Elliptocytosis 2 (EL2), Erythrocyte alpha spectrin, Erythroid alpha-spectrin, HPP, HS3, Spectrin alpha erythrocytic 1, SPH3, SPTA1

Gene Symbol: SPTA1

Tissue Expression: Red blood cells

Poids moléculaire: 240 kDa

ID gène: 6708

UniProt: P02549

Pathways: Regulation of Actin Filament Polymerization