SPTBN1 anticorps

N° du produit ABIN7660160

L’anticorps Souris Monoclonal anti-SPTBN1 a été validé pour WB et IF. Il convient pour détecter SPTBN1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SPTBN1 anticorps (ABIN7660160)

Antigène: SPTBN1 (Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SPTBN1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: RG-26

Détail du produit anti-SPTBN1 anticorps

Fonction: Spectrin beta I (SPTB)(RG/26)

Attributs du produit: Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming a scaffolding and playing an important role in maintenance of plasma membrane integrity and cytoskeletal structure. In certain types of brain injury such as diffuse axonal injury, spectrin is irreversibly cleaved by the proteolytic enzyme calpain, destroying the cytosketelon. Spectrin cleavage causes the membrane to form blebs and ultimately to be degraded, usually leading to cell death. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Red cell membranes

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: Jurkat whole cell lysate (WB). Human colon carcinoma tissue (IHC).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur SPTBN1

Antigène: SPTBN1 (Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))

Autre désignation: Spectrin beta I

Sujet:

Synonyms: beta-I spectrin, EL3, erythrocyte, HS2, SPTB1, HSPTB1, membrane cytoskeletal protein, spectrin beta (erythrocytic)

Gene Symbol: SPTB

Poids moléculaire: 246 kDa

ID gène: 6710

UniProt: O15020

Pathways: Regulation of Actin Filament Polymerization, Protein targeting to Nucleus