TSHB anticorps

N° du produit ABIN7660831

Cet anticorps Souris Monoclonal détecte spécifiquement TSHB dans IHC et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour TSHB anticorps (ABIN7660831)

Antigène: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TSHB est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: TSHb-1317

Détail du produit anti-TSHB anticorps

Fonction: Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker)(TSHb/1317)

Attributs du produit: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH) follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human TSH beta fragment

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: Normal pituitary or its tumor.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, no BSA, no azide

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Store at -20 °C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur TSHB

Antigène: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Autre désignation: Thyroid Stimulating Hormone, beta

Sujet:

Synonyms: CHNG4, Thyroid stimulating hormone beta subunit, Thyroid stimulating hormone, beta precursor, Thyrotropin beta subunit, TSHB

Gene Symbol: TSHB

Poids moléculaire: 16 kDa

ID gène: 7252

UniProt: P01222

Pathways: Thyroid Hormone Synthesis, Peptide Hormone Metabolism