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UPK1A anticorps (AA 114-173) (CF®405S)

L’anticorps Souris Monoclonal anti-UPK1A a été validé pour . Il convient pour détecter UPK1A dans des échantillons de Humain.
N° du produit ABIN7661615

Aperçu rapide pour UPK1A anticorps (AA 114-173) (CF®405S) (ABIN7661615)

Antigène

Voir toutes UPK1A Anticorps
UPK1A (Uroplakin 1a (UPK1A))

Reactivité

  • 36
  • 3
  • 1
Humain

Hôte

  • 23
  • 15
Souris

Clonalité

  • 23
  • 15
Monoclonal

Conjugué

  • 16
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Cet anticorp UPK1A est conjugé à/à la CF®405S

Application

Veuillez nous consulter SVP

Clone

UPK1A-2923
  • Épitope

    • 23
    • 8
    • 4
    • 3
    • 1
    • 1
    AA 114-173

    Fonction

    Uroplakin 1A (Urothelial Differentiation Marker)(UPK1A/2923), CF405S conjugate

    Attributs du produit

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Recombinant fragment (around aa 114-173) of human Uroplakin 1A (UPK1A) protein

    Isotype

    IgG2b, kappa
  • Indications d'application

    For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

    Commentaires

    Positive Control: Urinary Bladder.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % BSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    UPK1A (Uroplakin 1a (UPK1A))

    Autre désignation

    Uroplakin 1A

    Sujet

    Synonyms: UP1A, UPIA, UPKA, TSPAN21

    Gene Symbol: UPK1A

    Poids moléculaire

    29 kDa

    ID gène

    11045

    UniProt

    O00322
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