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UPK1A anticorps (AA 114-173) (CF®740)

Cet anticorps anti-UPK1A est un anticorps Souris Monoclonal détectant UPK1A dans IHC et IHC (fp). Adapté pour Humain.
N° du produit ABIN7661637

Aperçu rapide pour UPK1A anticorps (AA 114-173) (CF®740) (ABIN7661637)

Antigène

Voir toutes UPK1A Anticorps
UPK1A (Uroplakin 1a (UPK1A))

Reactivité

  • 35
  • 3
  • 1
Humain

Hôte

  • 22
  • 15
Souris

Clonalité

  • 22
  • 15
Monoclonal

Conjugué

  • 16
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Cet anticorp UPK1A est conjugé à/à la CF®740

Application

  • 22
  • 17
  • 14
  • 13
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone

UPK1A-2925
  • Épitope

    • 22
    • 8
    • 4
    • 3
    • 1
    • 1
    AA 114-173

    Fonction

    Uroplakin 1A (Urothelial Differentiation Marker)(UPK1A/2925), CF740 conjugate

    Attributs du produit

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Recombinant fragment (around aa 114-173) of human Uroplakin 1A (UPK1A) protein

    Isotype

    IgG1, kappa
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    Positive Control: Urinary Bladder.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % rBSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    UPK1A (Uroplakin 1a (UPK1A))

    Autre désignation

    Uroplakin 1A

    Sujet

    Synonyms: UP1A, UPIA, UPKA, TSPAN21

    Gene Symbol: UPK1A

    Poids moléculaire

    29 kDa

    ID gène

    11045

    UniProt

    O00322
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