VEGF anticorps (CF®640R)
Aperçu rapide pour VEGF anticorps (CF®640R) (ABIN7661835)
Antigène
Voir toutes VEGF AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- VEGF (Vascular Endothelial Growth Factor)(VG1), CF640R conjugate
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Attributs du produit
- This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet-derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogène
- Human VEGF189 recombinant protein
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Positive Control: Tumor cells in astrocytomas, breast or ovarian carcinomas.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % BSA, 0.05 % azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from light
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Stock
- 4 °C
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Stockage commentaire
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Date de péremption
- 24 months
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- VEGF (Vascular Endothelial Growth Factor (VEGF))
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Autre désignation
- VEGF
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Sujet
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Synonyms: MVCD1, Vascular Endothelial Growth Factor A (VEGF-A), Vascular Permeability Factor (VPF), VEGFA
Gene Symbol: VEGFA
Tissue Expression: Endothelial cells
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Poids moléculaire
- 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing)
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ID gène
- 7422
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UniProt
- P15692
Antigène
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