Recombinant VLDLR anticorps (C-Term) (CF®740)

N° du produit ABIN7661871

Cet anticorps anti-VLDLR est un anticorps Lapin Monoclonal détectant VLDLR dans . Adapté pour Humain et Rat.

Aperçu rapide pour Recombinant VLDLR anticorps (C-Term) (CF®740) (ABIN7661871)

Antigène: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp VLDLR est conjugé à/à la CF®740

Application: Veuillez nous consulter SVP

Clone: VLDLR-2896R

Détail du produit anti-VLDLR anticorps (CF®740)

Épitope: C-Term

Fonction: VLDL-Receptor (Very Low Density Lipoprotein Receptor)(VLDLR/2896R), CF740 conjugate

Attributs du produit: VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human VLDLR fragment from c-terminal

Isotype: IgG

Information d'application

Indications d'application: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Commentaires:

Positive Control: HeLa or U-251 cells. Pancreas, Cerebellum, Heart or Skeletal Muscle.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur VLDLR

Antigène: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Autre désignation: VLDL Receptor

Sujet:

Synonyms: Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR

Gene Symbol: VLDLR

Poids moléculaire: 143-161 kDa

ID gène: 7436

UniProt: P98155

Pathways: Cellular Response to Molecule of Bacterial Origin