WT1 anticorps (CF®488A)
Aperçu rapide pour WT1 anticorps (CF®488A) (ABIN7662048)
Antigène
Voir toutes WT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker), CF488A conjugate
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Attributs du produit
- Recognizes a 47-55 kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogène
- Recombinant human WT1 protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Positive Control: K562 cells. Wilm's Tumor, mesothelioma or fetal kidney.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % BSA, 0.05 % azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from light
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Stock
- 4 °C
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Stockage commentaire
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Date de péremption
- 24 months
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- WT1 (Wilms Tumor 1 (WT1))
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Autre désignation
- Wilms Tumor 1
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Sujet
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Synonyms: WT1, AWT1, FWT1, GUD, NPHS4, WAGR, Wilms tumor 1
Gene Symbol: WT1
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Poids moléculaire
- 47-55 kDa
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ID gène
- 7490
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UniProt
- P19544
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Pathways
- Tube Formation
Antigène
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