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Cytokeratin 1 anticorps (AA 141-240)

KRT1 Reactivité: Humain, Souris, Rat, Boeuf (Vache) WB, ELISA, FACS, IHC (p), ICC, IHC (fro), IF (p), IF (cc) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN733343
  • Antigène Voir toutes Cytokeratin 1 (KRT1) Anticorps
    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
    Épitope
    • 21
    • 16
    • 15
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 141-240
    Reactivité
    • 96
    • 56
    • 42
    • 23
    • 16
    • 13
    • 9
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache)
    Hôte
    • 76
    • 43
    • 1
    Lapin
    Clonalité
    • 69
    • 51
    Polyclonal
    Conjugué
    • 49
    • 15
    • 10
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Cytokeratin 1 est non-conjugé
    Application
    • 81
    • 54
    • 33
    • 29
    • 26
    • 26
    • 25
    • 19
    • 16
    • 13
    • 13
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
     Réactivité croisée
    Boeuf (Vache), Humain, Souris, Rat
    Homologie
    Dog,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human pan cytokeratin
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Yang, Li, Qi, Li, Zhou, Qing, Zhang, Gao: "lncRNA H19 is involved in TGF-β1-induced epithelial to mesenchymal transition in bovine epithelial cells through PI3K/AKT Signaling Pathway." dans: PeerJ, Vol. 5, pp. e3950, (2017) (PubMed).

    Wang, Jin, Fan, Wang, Xing, Niu: "Anti-proliferative activities of finasteride in benign prostate epithelial cells require stromal fibroblasts and c-Jun gene." dans: PLoS ONE, Vol. 12, Issue 2, pp. e0172233, (2017) (PubMed).

    Chen, Zheng, Liu, Shi, Qi: "Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." dans: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).

    Li, Wang, Liu, Tu, He, Wang, Han, Li, Li, Tao, Cai: "Identification of apoptotic cells in the thymus of piglets infected with highly pathogenic porcine reproductive and respiratory syndrome virus." dans: Virus research, Vol. 189, pp. 29-33, (2014) (PubMed).

    Li, Jia, Jia, Shi, Li, Ye, Wang, Xiong, Wang, Li: "Enrichment of Oct3/4-positive cells from a human bronchial epithelial cell line." dans: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 121, Issue 7, pp. 612-25, (2013) (PubMed).

  • Antigène
    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
    Autre désignation
    Cytokeratin (KRT1 Produits)
    Synonymes
    anticorps CK1, anticorps EHK, anticorps EHK1, anticorps EPPK, anticorps K1, anticorps KRT1A, anticorps NEPPK, anticorps Krt-2.1, anticorps Krt2-1, anticorps Krt86, anticorps KRT1, anticorps Kb1, anticorps KER1, anticorps CK-1, anticorps Keratin-1, anticorps keratin 1, anticorps KRT1, anticorps Krt1
    Sujet

    Synonyms: pan-cytokeratin, pan-CK, pan CK, P-CK, wide spectrum Cytokeratin, Cytokeratins, [cytokeratins 1, 2,4,5,6,7,8,71,72,75,78].

    Background: Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The cytokeratins are encoded by a family encompassing 30 genes. Among them, 20 are epithelial genes and the remaining 10 are specific for trichocytes. In the cytoplasm, the keratin filaments conform a complex network which extends from the surface of the nucleus to the cell membrane. Numerous accessory proteins are involved in the genesis and maintenance of such structure. This association between the plasma membrane and the nuclear surface provides important implications for the organization of the cytoplasm and cellular communication mechanisms. Apart from the relatively static functions provided in terms of supporting the nucleus and providing tensile strength to the cell, the cytokeratin networks undergo rapid phosphate exchanges mediated depolymerization, with important implications in the more dynamic cellular processes such as mitosis and post-mitotic period, cell movement and differentiation. Cytokeratins interact with desmosomes and hemidesmosomes, thus collaborating to cell-cell adhesion and basal cell-underlying connective tissue connection.

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