CD180 anticorps

N° du produit ABIN7669988

Cet anticorps anti-CD180 est un anticorps Souris Monoclonal détectant CD180 dans FACS. Adapté pour Humain.

Aperçu rapide pour CD180 anticorps (ABIN7669988)

Antigène: CD180 (CD180 Molecule (CD180))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD180 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: G28-8

Détail du produit anti-CD180 anticorps

Fonction: Purified Anti-Human CD180 Antibody[G28-8]

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: avoid freeze / thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur CD180

Antigène: CD180 (CD180 Molecule (CD180))

Autre désignation: CD180

Sujet: LY64,RP105,CD180,Ly78,CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.

UniProt: Q99467

Pathways: Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades