CD180 anticorps
Aperçu rapide pour CD180 anticorps (ABIN7669988)
Antigène
Voir toutes CD180 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Purified Anti-Human CD180 Antibody[G28-8]
-
Isotype
- IgG1, kappa
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- ≥ 1 mg/mL
-
Buffer
- Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- avoid freeze / thaw cycles.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
-
Date de péremption
- 12 months
-
-
- CD180 (CD180 Molecule (CD180))
-
Autre désignation
- CD180
-
Sujet
- LY64,RP105,CD180,Ly78,CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.
-
UniProt
- Q99467
-
Pathways
- Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Antigène
-