Interleukin 17a anticorps

N° du produit ABIN7670182

L’anticorps anti-Interleukin 17a Monoclonal Souris est utilisé pour la détection de Interleukin 17a dans des échantillons de Souris. Il a été validé pour ICFC.

Aperçu rapide pour Interleukin 17a anticorps (ABIN7670182)

Antigène: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Interleukin 17a est non-conjugé

Application: Intracellular Flow Cytometry (ICFC)

Clone: 17F3

Détail du produit anti-Interleukin 17a anticorps

Fonction: AF/LE Purified Anti-Mouse IL-17A Antibody[17F3]

niveau d'endotoxine: Low Endotoxin

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: ≥ 1 mg/mL

Buffer: Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.

Agent conservateur: Azide free

Conseil sur la manipulation: avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Date de péremption: 12 months

Détails sur Interleukin 17a

Antigène: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Autre désignation: IL-17A

Sujet: Interleukin-17A,Il17a,Ctla9,The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-18A?in vivo.

UniProt: Q62386