KLRG1 anticorps

N° du produit ABIN7670189

Cet anticorps anti-KLRG1 est un anticorps Golden Syrian Hamster Monoclonal détectant KLRG1 dans FACS. Adapté pour Humain et Souris.

Aperçu rapide pour KLRG1 anticorps (ABIN7670189)

Antigène: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Reactivité: Humain, Souris

Hôte: Golden Syrian Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp KLRG1 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: 2F1

Détail du produit anti-KLRG1 anticorps

Fonction: AF/LE Purified Anti-Human/Mouse KLRG-1 Antibody[2F1]

niveau d'endotoxine: Low Endotoxin

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: ≥ 1 mg/mL

Buffer: Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.

Agent conservateur: Azide free

Conseil sur la manipulation: avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Date de péremption: 12 months

Détails sur KLRG1

Antigène: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Autre désignation: KLRG-1

Sujet: MAFA, 2F1-Ag,Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag).? KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3.? It is composed of a homodimer of glycosylated 30-38 kD subunits.? Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells.? KLRG1 is also expressed on subsets of CD8+?and CD4+?cells, including CD4+?and CD8+?effector/memory cells, potent regulatory CD4+?T cells.? KLRG1 may be involved in regulating NK cell homeostasis.? KLRG2 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

UniProt: Q96E93, O88713