Integrin beta 7 anticorps (PE)

N° du produit ABIN7670235

Cet anticorps Rat Monoclonal détecte spécifiquement Integrin beta 7 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour Integrin beta 7 anticorps (PE) (ABIN7670235)

Antigène: Integrin beta 7 (ITGB7)

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 7 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: FIB504

Détail du produit anti-Integrin beta 7 anticorps (PE)

Fonction: PE Anti-Human Integrin β7 Antibody[FIB504]

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 5 μL/tests

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Conseil sur la manipulation: Please protected from prolonged exposure to light and do not freeze.

Stock: 4 °C

Stockage commentaire: This product can be stored at 2-8°C for 12 months.

Date de péremption: 12 months

Détails sur Integrin beta 7

Antigène: Integrin beta 7 (ITGB7)

Autre désignation: Integrin beta7

Sujet: CEACAM1a,Bgp,Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.

UniProt: P31809

Pathways: Integrin Complex