HLA DQ anticorps (PE,Cy5.5)

N° du produit ABIN7670251

L’anticorps Souris Monoclonal anti-HLA DQ a été validé pour FACS. Il convient pour détecter HLA DQ dans des échantillons de Humain.

Aperçu rapide pour HLA DQ anticorps (PE,Cy5.5) (ABIN7670251)

Antigène: HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA DQ est conjugé à/à la PE,Cy5.5

Application: Flow Cytometry (FACS)

Clone: 1a3

Détail du produit anti-HLA DQ anticorps (PE,Cy5.5)

Fonction: PE/Cyanine5.5 Anti-Human HLA-DQ Antibody[1a3]

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 5 μL/tests

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant

Conseil sur la manipulation: Please protected from prolonged exposure to light and do not freeze.

Stock: 4 °C

Stockage commentaire: This product can be stored at 2-8°C for 12 months.

Date de péremption: 12 months

Détails sur HLA DQ

Antigène: HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

Autre désignation: HLA-DQ

Sujet: MHC class II DQ monomorphic antigen,MHC II,HLA-DQ is also known as MHC class II DQ monomorphic antigen. The major histocompatibility complex is composed of two heterodimeric glycoproteins (α and β chains) with apparent molecular weights of 27 and 32 kD. In contrast to other MHC class II molecules, both polypeptide chains of HLA-DQ are polymorphic, with the α chain showing an extremely high degree of polymorphism. HLA-DQ is expressed on B cells in the peripheral blood, and weakly expressed on activated T cells and some monocytes. HLA-DQ is absent on hematopoietic progenitors, resting T cells, erythrocytes, and platelets. HLA-DQ is expressed after HLA-DR and HLA-DP in hematopoietic development. HLA-DQ presents peptide fragments mainly from degraded intravesicular and extracellular proteins to CD4+ T lymphocytes. Specific alleles of HLA-DQ have been linked to the pathogenesis of several autoimmune diseases (including diabetes), both as a susceptibility and resistance factor depending on the particular polymorphism.

UniProt: P01906