Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C Valid for 1 month or -20°C Valid for 12 months
Date de péremption
12 months
Antigène
CCL21
(Chemokine (C-C Motif) Ligand 21 (CCL21))
Autre désignation
CCL21/6Ckine
Sujet
TCA,Scya,Beta-Chemokine Exodus,Thymus-Derived Chemotactic Agent,6Ckine,Beta-Chemokine Exodus-2,C-C Motif Chemokine 21a,Small-Inducible Cytokine A21a,TCA4,Thymus-Derived Chemotactic Agent 4,Scya21,Scya21a,Ccl21a,C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine beta (CCchemokine) family. Mouse CCL21 cDNA encodes a 133 amino acid residue protein with a 23 residue signalpeptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms whileCCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 andCXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro forthymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 showspreferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes tosecondary lymphoid organs.