Endoglin anticorps

N° du produit ABIN7670592

L’anticorps Lapin Polyclonal anti-Endoglin a été validé pour ELISA. Il convient pour détecter Endoglin dans des échantillons de Humain.

Aperçu rapide pour Endoglin anticorps (ABIN7670592)

Antigène: Endoglin (ENG)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Endoglin est non-conjugé

Application: ELISA

Détail du produit anti-Endoglin anticorps

Fonction: Endoglin/CD105 Polyclonal Antibody(Capture/Detector)

Purification: Antigen Affinity Purification

Immunogène: Recombinant Human Endoglin/CD105 protein expressed by E.coli

Isotype: IgG

Information d'application

Indications d'application: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur Endoglin

Antigène: Endoglin (ENG)

Autre désignation: Endoglin/CD105

Sujet: ENG,CD105,EndogLin,END,Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis.Required for normal structure and integrity of adult vasculature.Regulates the migration of vascular endothelial cells.Required for normal extraembryonic angiogenesis and for embryonic heart development.May regulate endothelial cell shape changes in response to blood flow,which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors.Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3.

UniProt: P17813