IL32 anticorps

N° du produit ABIN7670668

Cet anticorps anti-IL32 est un anticorps Rat Monoclonal détectant IL32 dans ELISA (Detection). Adapté pour Humain.

Aperçu rapide pour IL32 anticorps (ABIN7670668)

Antigène: IL32 (Interleukin 32 (IL32))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL32 est non-conjugé

Application: ELISA (Detection)

Clone: 4D9

Détail du produit anti-IL32 anticorps

Fonction: IL-32 Monoclonal Antibody(Detector)

Purification: Protein A/G Purification

Immunogène: Recombinant Human IL-32 protein expressed by E.coli

Isotype: IgG1

Information d'application

Indications d'application: ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur IL32

Antigène: IL32 (Interleukin 32 (IL32))

Autre désignation: IL-32

Sujet: Interleukin-32,IL-32,Natural killer cells protein 4,Tumor necrosis factor alpha-inducing factor,IL32,NK4,TAIF,IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active, although all isoforms are biologically active. IL-32, a cytokine produced mainly by T, natural killer, and epithelial cells induces significant amounts of TNFalpha and MIP-2 and increases the production of both cytokines in a dose-dependent manner. IL-32 has been implicated in inflammatory disorders, Mycobacterium tuberculosis infections, inflammatory bowel disease, and influenza A virus infection, as well as in some autoimmune diseases, such as rheumatoid arthritis, ulcerative colitis, and in the human stomach cancer, human lung cancer, and breast cancer tissues. Thus, IL-32 expression might be valuable as a biomarker for cancer.

UniProt: P24001