SIGLEC9 anticorps (APC)

N° du produit ABIN7672709

Cet anticorps Souris Monoclonal détecte spécifiquement SIGLEC9 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour SIGLEC9 anticorps (APC) (ABIN7672709)

Antigène: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIGLEC9 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: K8

Détail du produit anti-SIGLEC9 anticorps (APC)

Fonction: APC Anti-Human CD329 Antibody

Purification: 0

Pureté: 0

Isotype: IgG1, kappa

Information d'application

Indications d'application: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: 4 °C

Stockage commentaire: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur SIGLEC9

Antigène: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Autre désignation: CD329

Sujet:

Synonyms: Siglec-9|Sialic acid-binding Ig-like lectin-9,

Background: Siglecs are cell surface receptors belonging to the immunoglobulin superfamily that recognize sugar antigens. The extracellular domain of siglec-9 contains an IgV region, which binds sialic acid, followed by two IgC regions. Siglec 9 and siglec 6-8,10-12 are CD33 (siglec 3) like siglecs, which have two ITIMs in the cytoplasmic tails, suggesting their functional involvement in signal transduction. It is highly expressed on neutrophils and monocytes, and at lower levels on the subpopulations of T and B lymphocytes and NK cells. Siglec-9 plays a role in negative regulation of T cell activation, and it also affects neutrophil apoptosis.

Poids moléculaire: 0

ID gène: 27180

UniProt: Q9Y336