Integrin beta 7 anticorps (APC)

N° du produit ABIN7672783

Cet anticorps anti-Integrin beta 7 est un anticorps Rat Monoclonal détectant Integrin beta 7 dans FACS. Adapté pour Humain et Souris.

Aperçu rapide pour Integrin beta 7 anticorps (APC) (ABIN7672783)

Antigène: Integrin beta 7 (ITGB7)

Reactivité: Humain, Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 7 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: FIB21

Détail du produit anti-Integrin beta 7 anticorps (APC)

Fonction: APC Anti-Human/Mouse Integrin β7 Antibody

Purification: 0

Pureté: 0

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: 4 °C

Stockage commentaire: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur Integrin beta 7

Antigène: Integrin beta 7 (ITGB7)

Autre désignation: Integrin beta7

Sujet:

Synonyms: β7 Integrin|integrin βp|ITGB7

Background: Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.

Poids moléculaire: 0

ID gène: 3695

UniProt: P26010, P26011

Pathways: Integrin Complex